Active ingredientSelonsertibCat. No. P-S028-001CAS 1448428-04-3Family · Pharmaceutical analytical standards
Selonsertib
An inhibitor of the ASK1 kinase studied for non-alcoholic steatohepatitis (NASH) with advanced fibrosis and cirrhosis: in 2019 two large phase 3 trials did not show the expected benefit over placebo. This family brings together the active ingredient.
Did you know?ASK1 stands for apoptosis signal-regulating kinase 1: it is a sensor of cell stress, kept switched off by thioredoxin and switched on by oxidative stress and the build-up of misfolded proteins.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.