Family · Pharmaceutical analytical standards
Sipatrigine
A lamotrigine derivative that blocks neuronal sodium and calcium channels, studied in the 1990s as a neuroprotective agent against damage from ischaemic stroke: in rats it reduced the size of the brain infarct. This family brings together the active ingredient.
Did you know?In slices of rat brain it curbs the release of glutamate and aspartate, two excitatory amino acids, and lowers the firing rate of neurons.
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