Family · Pharmaceutical analytical standards
Staurosporine
An indolocarbazole alkaloid made by the bacterium Streptomyces staurosporeus, discovered in 1977 by Satoshi Ōmura's group: it is a very potent protein kinase inhibitor, widely used as a research tool. This family brings together the active ingredient, nitrosamines and other impurities.
Did you know?It blocks so many kinases that it never became a medicine, but in the laboratory it is used to trigger apoptosis; midostaurin was developed from its structure.
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