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Family · Pharmaceutical analytical standards

Terlipressin

A peptide analogue of vasopressin synthesised in the mid-1960s in Czechoslovakia by Kasafirek, Rábek, Rudinger and Šorm: it narrows the blood vessels of the splanchnic area, is used against bleeding oesophageal varices and, in the United States since 2022, for hepatorenal syndrome. This family brings together the active ingredient.

Did you know?It is a "hormonogen": the three glycines added at the head of the chain are slowly cleaved off by enzymes, gradually releasing lysine vasopressin and prolonging its effect.

TerlipressinGo to the active ingredient →
TerlipressinActive ingredientTerlipressinCat. No. P-T065-001CAS 14636-12-5

EDQM standards 2

The official European Pharmacopoeia standards for this family.

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