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Family · Pharmaceutical analytical standards

Tioguanine

An antimetabolite analogue of guanine, developed between 1949 and 1951 by Gertrude Elion and George Hitchings; it is taken by mouth mainly for acute leukaemias, especially acute myeloid leukaemia. This family brings together other impurities.

Did you know?Elion had joined Hitchings's laboratory in 1944 as his assistant; in 1988 the two received the Nobel Prize in Physiology or Medicine, shared with Sir James Black.

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