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Family · Pharmaceutical analytical standards

Tolafentrine

A dual inhibitor of phosphodiesterases 3 and 4, studied as a possible medicine for pulmonary hypertension and chronic obstructive pulmonary disease (COPD); its clinical development stopped at phase 2. This family brings together the active ingredient.

Did you know?It shares its mechanism with ensifentrine, approved in the United States in 2024 for COPD: blocking PDE3 widens the airways, while blocking PDE4 dampens inflammation.

TolafentrineGo to the active ingredient →
TolafentrineActive ingredientTolafentrineCat. No. P-T146-001CAS 139308-64-8

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