Family · Pharmaceutical analytical standards
Tolimidone
A molecule born around 1980 as a candidate against stomach ulcers, because it stimulates mucus secretion in the stomach, and then abandoned; decades later it was rediscovered as an allosteric activator of Lyn kinase and studied in type 2 diabetes. This family brings together the active ingredient and other impurities.
Did you know?It is an example of drug repurposing: once the patent had expired, it was picked up again through a phenotypic screen and turned out to be an insulin sensitiser that does not act on PPAR-gamma, the target of the glitazones.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
