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Trofinetide

A synthetic analogue of the tripeptide glycine-proline-glutamate, which the brain cuts from the growth factor IGF-1; approved in the United States in March 2023, it is the first authorised treatment for Rett syndrome, from two years of age. This family brings together the active ingredient and other impurities.

Did you know?Before reaching Rett syndrome it had been studied as a possible treatment for stroke; it also gave positive results in a phase II trial in fragile X syndrome.

TrofinetideGo to the active ingredient →
TrofinetideActive ingredientTrofinetideCat. No. P-T224-001CAS 853400-76-7

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