Family · Pharmaceutical analytical standards
Upadacitinib
A selective JAK1 kinase inhibitor, approved in 2019 in the United States and Europe for rheumatoid arthritis, and later for psoriatic arthritis, atopic dermatitis, ulcerative colitis, Crohn's disease and axial spondyloarthritis. This family brings together the active ingredient, metabolites, labelled standards, nitrosamines and other impurities.
Did you know?It is a second-generation JAK inhibitor that favours JAK1: it is about 74 times more selective for JAK1 than for JAK2 and 58 times more than for JAK3.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
