Family · Pharmaceutical analytical standards
Vismodegib
An inhibitor of the Hedgehog signalling pathway that blocks the Smoothened receptor; approved in the United States in January 2012 as the first drug targeting this pathway, for advanced basal cell carcinoma. This family brings together the active ingredient, labelled standards and other impurities.
Did you know?The Hedgehog pathway takes its name from a gene found in 1980 in the fruit fly by Christiane Nüsslein-Volhard and Eric Wieschaus: the mutant larvae were covered in spikes like a hedgehog.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
