Family · Pharmaceutical analytical standards
Voclosporin
A calcineurin inhibitor and analogue of ciclosporin, discovered in the 1990s and approved for lupus nephritis in the United States in 2021 and in the European Union in 2022. This family brings together the active ingredient, metabolites, labelled standards, nitrosamines and other impurities.
Did you know?It was the first oral treatment for lupus nephritis approved in the United States; compared with ciclosporin it changes the side chain of just one amino acid, which alters how it binds its target.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
