Family · Pharmaceutical analytical standards
Vorinostat
The first histone deacetylase (HDAC) inhibitor approved by the FDA, in 2006, for the skin manifestations of cutaneous T-cell lymphoma that persists or returns after other therapies. This family brings together the active ingredient, labelled standards and other impurities.
Did you know?It stems from a finding Charlotte Friend published in 1971: the solvent DMSO made mouse leukaemia cells mature into red blood cells; Paul Marks and Ronald Breslow sought more potent analogues and arrived at SAHA.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
