Family · Pharmaceutical analytical standards
Zosuquidar
An investigational inhibitor of P-glycoprotein, the pump that expels chemotherapy drugs from cancer cells; in the 2000s it was studied to overcome drug resistance in acute myeloid leukaemia, but development stopped after a phase III trial in 2010. This family brings together the active ingredient and labelled standards.
Did you know?Its structure contains a small three-carbon ring bearing two fluorine atoms, built with difluorocarbene, a chemical species so unstable that it has to be generated directly in the reaction mixture.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
