Family · Pharmaceutical analytical standards
Zotarolimus
A semi-synthetic derivative of sirolimus in which a tetrazole ring replaces a hydroxyl group, designed for drug-eluting coronary stents: it curbs the cell growth that narrows the artery again. In the US the first stents releasing it were approved in 2008. This family brings together the active ingredient.
Did you know?It descends from rapamycin, isolated in 1972 from Streptomyces hygroscopicus bacteria collected on Easter Island: the name comes from Rapa Nui, the island's native name.
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