Active ingredientTacrineCat. No. P-T003-001CAS 321-64-2
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Impurity or related compound · Tacrine family
Pharmaceutical analytical standard1-Hydroxy Tacrine
Synonyms: Velnacrine, 9-amino-1,2,3,4-tetrahydroacridin-1-ol, Hydroxytacrine, Velnacrina, Velnacrinum
- Cat. No.
- P-T003-004
- CAS
- 124027-47-0
- Alternative CAS
- 136134-45-7 (hydrochloride)
- 104675-29-8 (alternative CAS, same compound)
- 121445-24-7 (alternative CAS, same compound)
- 121445-26-9 (alternative CAS, same compound)
- Formula
- C13H14N2O
- Molecular weight
- 214.27 g/mol
- Category
- Impurity or related compound
Family: Tacrine
An acetylcholinesterase inhibitor that raises acetylcholine levels in the brain: in 1993 it became the first drug approved by the FDA for Alzheimer's disease, paving the way for later treatments.
Did you know?It had been synthesised as early as 1949 by the chemist Adrien Albert at the University of Sydney, more than forty years before it became a medicine for memory.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Tacrine family
Active ingredientTacrineCat. No. P-T003-001CAS 321-64-2
Isotopically labelled1-Hydroxy Tacrine-d4Cat. No. P-T003-002CAS 1246911-78-3
Isotopically labelled1-Hydroxy Tacrine-d4 HClCat. No. P-T003-003CAS 1246816-08-9Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.