Active ingredientLisinoprilCat. No. P-L075-001CAS 76547-98-3
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Impurity or related compound · Lisinopril family
Pharmaceutical analytical standard2,2,2-Trifluoroethyl formate
Synonyms: Lisinopril Impurity 12 (2,2,2-trifluoroethyl formate), Trifluoroethyl formate, TFEF, Formic Acid 2,2,2-Trifluoroethyl Ester, Ethanol, 2,2,2-trifluoro-, 1-formate
- Cat. No.
- P-L075-018
- CAS
- 32042-38-9
- Alternative CAS
- N/A
- Formula
- C3H3F3O2
- Molecular weight
- 128.05 g/mol
- Category
- Impurity or related compound
Family: Lisinopril
An ACE inhibitor used for high blood pressure, heart failure and after heart attacks, patented in 1978 and approved in the United States in 1987; in 2023 it was the fourth most prescribed medicine in the US.
Did you know?Its name recalls lysine, the amino acid built into its structure: unlike almost all ACE inhibitors it is not a prodrug, and it is excreted unchanged in the urine.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Lisinopril family
Active ingredientLisinoprilCat. No. P-L075-001CAS 76547-98-3
Active ingredientLisinopril DihydrateCat. No. P-L075-002CAS 83915-83-7
Pharmacopoeial impurityLisinopril EP Impurity FCat. No. P-L075-003CAS 1132650-67-9
Pharmacopoeial impurityLisinopril EP Impurity ACat. No. P-L075-004CAS 1012-05-1
Pharmacopoeial impurityLisinopril EP Impurity CCat. No. P-L075-005CAS 328385-86-0
Pharmacopoeial impurityLisinopril EP Impurity C HClCat. No. P-L075-006
Pharmacopoeial impurityLisinopril EP Impurity DCat. No. P-L075-007CAS 219677-82-4
Pharmacopoeial impurityLisinopril EP Impurity D HClCat. No. P-L075-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.