Active ingredientFlupirtineCat. No. P-F095-001CAS 56995-20-1
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Impurity or related compound · Flupirtine family
Pharmaceutical analytical standard2,6-Dichloro-3-nitropyridine
Synonyms: Flupirtine Impurity H, Pyridine, 2,6-dichloro-3-nitro-, Dichloronitropyridine
- Cat. No.
- P-F095-005
- CAS
- 16013-85-7
- Alternative CAS
- N/A
- Formula
- C5H2Cl2N2O2
- Molecular weight
- 192.98 g/mol
- Category
- Impurity or related compound
Family: Flupirtine
A non-opioid analgesic of the aminopyridine family, approved in Europe in 1984 for pain: it works by opening potassium channels in nerve cells. In the European Union it was withdrawn from the market in 2018.
Did you know?It was the first KCNQ (Kv7) potassium channel opener to enter medical use; the same research programme produced retigabine, a close relative that became an antiepileptic.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Flupirtine family
Active ingredientFlupirtineCat. No. P-F095-001CAS 56995-20-1
Active ingredientFlupirtine MaleateCat. No. P-F095-002CAS 75507-68-5
Isotopically labelledAcetylated Flupirtine-d4 HClCat. No. P-F095-003CAS 1216989-17-1
Isotopically labelledFlupirtine-d4 HClCat. No. P-F095-004CAS 1324717-75-0![5-[(4-Fluorobenzyl)amino]-1H-imidazo[4,5-b]pyridin-2(3H)-one](https://img.vitasanlabs.com/vsl-struct/P-F095-006.svg?v=41e934f030)
Impurity5-[(4-Fluorobenzyl)amino]-1H-imidazo[4,5-b]pyridin-2(3H)-oneCat. No. P-F095-006CAS 951624-49-0
Impurity6-Amino-2-(4-fluorobenzylamino)-3-nitropyridineCat. No. P-F095-007CAS 1506942-35-3
ImpurityAcetylated FlupirtineCat. No. P-F095-008CAS 88874-11-7
ImpurityFlupirtine Impurity 1Cat. No. P-F095-009Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.