Active ingredientFenspirideCat. No. P-F031-001CAS 5053-06-5
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Impurity or related compound · Fenspiride family
Pharmaceutical analytical standard2-Hydroxy Fenspiride
Synonyms: 8-[2-(2-Hydroxyphenyl)ethyl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one
- Cat. No.
- P-F031-005
- CAS
- 441781-21-1
- Alternative CAS
- N/A
- Formula
- C15H20N2O3
- Molecular weight
- 276.34 g/mol
- Category
- Impurity or related compound
Family: Fenspiride
A spiro compound of the oxazolidinone family, with anti-inflammatory action on the airways: used for cough due to lung diseases and for inflammation of the nose, throat and bronchi, until 2019 it was authorised in several European countries, including France, Poland and Romania.
Did you know?It acts on several targets at once: it blocks alpha-1 adrenergic receptors and histamine H1 receptors and inhibits several phosphodiesterases, the enzymes that regulate tissue tone and inflammation.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Fenspiride family
Active ingredientFenspirideCat. No. P-F031-001CAS 5053-06-5
Active ingredientFenspiride HClCat. No. P-F031-002CAS 5053-08-7
Isotopically labelledFenspiride-d5Cat. No. P-F031-003CAS 1246911-67-0
NitrosamineN-Nitroso FenspirideCat. No. P-F031-004
Impurity3-Hydroxy FenspirideCat. No. P-F031-006CAS 441781-23-3
ImpurityFenspiride Impurity ACat. No. P-F031-007CAS 23808-42-6
Impurity4-Hydroxy FenspirideCat. No. P-F031-008CAS 441781-25-5
ImpurityFenspiride N-OxideCat. No. P-F031-009CAS 210690-26-9Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.