Active ingredientSuvorexantCat. No. P-S139-001CAS 1030377-33-3
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Impurity or related compound · Suvorexant family
Pharmaceutical analytical standard2-Iodo-3-methylbenzoic acid
Synonyms: Suvorexant Impurity 31, Benzoic acid, 2-iodo-3-methyl-
- Cat. No.
- P-S139-010
- CAS
- 108078-14-4
- Alternative CAS
- N/A
- Formula
- C8H7IO2
- Molecular weight
- 262.05 g/mol
- Category
- Impurity or related compound
Family: Suvorexant
The first orexin receptor antagonist approved for insomnia, in the United States in 2014: rather than sedating the brain, it dampens the signal that keeps it awake.
Did you know?The name orexin comes from the Greek orexis, appetite: when these neuropeptides were discovered in 1998 they were thought to regulate mainly hunger; only later was their key role in wakefulness understood.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Suvorexant family
Active ingredientSuvorexantCat. No. P-S139-001CAS 1030377-33-3
Isotopically labelledSuvorexant-d6Cat. No. P-S139-002
Isotopically labelledSuvorexant-d6 (Racemic)Cat. No. P-S139-003
NitrosamineN-Nitroso Suvorexant Impurity 1Cat. No. P-S139-004
NitrosamineN-Nitroso Suvorexant Impurity 2Cat. No. P-S139-005
Impurity2-(2H-1,2,3-Triazol-2-yl)benzoic acidCat. No. P-S139-006CAS 1001401-62-2
Impurity2-Amino-3-methylbenzoic acidCat. No. P-S139-007CAS 4389-45-1
Impurity2-Bromo-3-methylbenzoic acidCat. No. P-S139-008CAS 53663-39-1Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.