Active ingredientCalcitriolCat. No. P-C010-001CAS 32222-06-3
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Impurity or related compound · Calcitriol family
Pharmaceutical analytical standard(24R)-Hydroxycalcitriol
Synonyms: Calcitetrol
- Cat. No.
- P-C010-009
- CAS
- 56142-94-0
- Alternative CAS
- N/A
- Formula
- C27H44O4
- Molecular weight
- 432.64 g/mol
- Category
- Impurity or related compound
Family: Calcitriol
The active form of vitamin D3 (1,25-dihydroxycholecalciferol): a true hormone, made mainly in the kidneys, that regulates calcium and phosphate. Identified in 1971, it has been used as a medicine since 1978 for chronic kidney disease and hypoparathyroidism.
Did you know?It also exists outside the human body: some plants, such as Solanum malacoxylon, contain glycoside forms of it, and cattle grazing on them, for example in Argentina and Brazil, can develop calcification of their tissues.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Calcitriol family
Active ingredientCalcitriolCat. No. P-C010-001CAS 32222-06-3
Pharmacopoeial impurityCalcitriol EP Impurity ACat. No. P-C010-002CAS 73837-24-8
Pharmacopoeial impurityCalcitriol EP Impurity BCat. No. P-C010-003CAS 66791-71-7
Pharmacopoeial impurityCalcitriol EP Impurity CCat. No. P-C010-004CAS 86307-44-0
Isotopically labelledCalcitriol EP Impurity A-d6Cat. No. P-C010-006
Isotopically labelledCalcitriol EP Impurity B-d6Cat. No. P-C010-007CAS 1883417-58-0
Isotopically labelledCalcitriol-d6Cat. No. P-C010-008CAS 78782-99-7
Impurity24-Homo CalcitriolCat. No. P-C010-011CAS 103656-40-2Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.