Active ingredientNaftidrofuryl Hydrogen OxalateCat. No. P-N009-001CAS 3200-06-4
Drag to rotate
Pharmacopoeial impurity · Naftidrofuryl family
Pharmaceutical analytical standard3-(1-Naphthyl)-2-Tetrahydrofurfurylpropionic Acid
Synonyms: Naftidrofuryl Impurity A, Tetrahydro-alpha-(1-naphthalenylmethyl)-2-furanpropanoic acid, 2-(naphthalen-1-ylmethyl)-3-(oxolan-2-yl)propanoic acid, Naphthidrofurylic acid, Tetrahydro-a-(1-naphthalenylmethyl)-2-furanpropanoic Acid, Tetrahydro-alpha-(1-naphthylmethyl)furan-2-propionic acid, Naftidrofuryl Impurity 1, NaphthylMethyltetrahydrofurfurylpropanoic acid, alpha-(1-Naphtylmethyl)tetrahydro-2-furanpropanoic acid, beta-(1-Naphthalene)-beta'-tetrahydrofuryl isobutyrate, Tetrahydro-beta-(1-nephthalenylmethyl)-2-furanpropionic acid
- Cat. No.
- P-N009-002
- CAS
- 25379-26-4
- Alternative CAS
- N/A
- Formula
- C18H20O3
- Molecular weight
- 284.35 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Naftidrofuryl
A vasodilator that blocks serotonin 5-HT2 receptors and improves blood flow; on the market since the late 1960s, it is used for intermittent claudication caused by peripheral arterial disease.
Did you know?Its official United States name is nafronyl. Besides blocking 5-HT2 receptors, it is thought to stimulate the Krebs cycle inside cells, boosting production of ATP, their energy currency.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- 3-(1-Naphthyl)-2-Tetrahydrofurfurylpropionic AcidBP 360
- Naftidrofuryl impurity A CRSEP Y0000120
More products in the Naftidrofuryl family
Active ingredientNaftidrofuryl Hydrogen OxalateCat. No. P-N009-001CAS 3200-06-4
Pharmacopoeial impurityNaftidrofuryl EP Impurity BCat. No. P-N009-003CAS 35997-58-1
Pharmacopoeial impurityNaftidrofuryl EP Impurity FCat. No. P-N009-004CAS 41359-72-2
ImpurityNaftidrofuryl Oxalate Impurity CCat. No. P-N009-006CAS 115025-99-5
ImpurityNaftidrofuryl Impurity CCat. No. P-N009-009Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.