Active ingredientPhenytoinCat. No. P-P097-001CAS 57-41-0
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Impurity or related compound · Phenytoin family
Pharmaceutical analytical standard3-Hydroxy Phenytoin
Synonyms: 5-(3'-Hydroxyphenyl)-5-phenylhydantoin, 5-(3-hydroxyphenyl)-5-phenylimidazolidine-2,4-dione, m-Hydroxydiphenylhydantoin
- Cat. No.
- P-P097-013
- CAS
- 30074-03-4
- Alternative CAS
- N/A
- Formula
- C15H12N2O3
- Molecular weight
- 268.27 g/mol
- Category
- Impurity or related compound
Family: Phenytoin
A hydantoin anticonvulsant, in use since 1938 against epileptic seizures: unlike the medicines of the time, it controlled seizures without strong sedation.
Did you know?First synthesised in 1908 by German chemist Heinrich Biltz, it sat in a drawer for almost thirty years until Merritt and Putnam, searching for non-sedating relatives of phenobarbital, discovered its anti-seizure effect.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Phenytoin family
Active ingredientPhenytoinCat. No. P-P097-001CAS 57-41-0
Active ingredientPhenytoin SodiumCat. No. P-P097-002CAS 630-93-3
Pharmacopoeial impurityPhenytoin EP Impurity BCat. No. P-P097-003CAS 134-81-6
Pharmacopoeial impurityPhenytoin EP Impurity CCat. No. P-P097-004CAS 3060-50-2
Pharmacopoeial impurityPhenytoin EP Impurity DCat. No. P-P097-005CAS 5157-15-3
Pharmacopoeial impurityPhenytoin EP Impurity ECat. No. P-P097-006CAS 6802-95-5
Pharmacopoeial impurityPhenytoin EP Impurity FCat. No. P-P097-007CAS 51169-17-6
Isotopically labelledPhenytoin EP Impurity A-d5Cat. No. P-P097-008CAS 2694-78-2Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.