Active ingredientClidinium BromideCat. No. P-C192-001CAS 3485-62-9
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Impurity or related compound · Clidinium family
Pharmaceutical analytical standard3-Quinuclidinyl benzilate
Synonyms: Clidinium Bromide Impurity 1, 1-azabicyclo[2.2.2]octan-3-yl 2-hydroxy-2,2-diphenylacetate, NSC 173698, Benzeneacetic acid, alpha-hydroxy-alpha-phenyl-, 1-azabicyclo(2.2.2)oct-3-yl ester, Benzilate, Quinuclidinyl, Quinuclidinyl Benzilate, R-(-)-3-Quinuclidinyl benzilate, Benzilic acid, 3-quinuclidinyl ester, (+-)-, Buzz, Agent BZ, r(-)-quinuclidinyl benzilate, beta-Quinuclidinyl benzilate, Substance 78, NSC 168347, r,s-(+/-)-quinuclidinyl benzilate
- Cat. No.
- P-C192-005
- CAS
- 6581-06-2
- Alternative CAS
- 13004-56-3 (hydrochloride)
- Formula
- C21H23NO3
- Molecular weight
- 337.42 g/mol
- Category
- Impurity or related compound
Family: Clidinium
A synthetic quaternary ammonium antimuscarinic that reduces gut motility and spasms: since the 1960s it has been used in a fixed combination with chlordiazepoxide for irritable bowel syndrome and as an adjunct in peptic ulcer.
Did you know?The combination joins two complementary effects: clidinium calms intestinal spasms, chlordiazepoxide the anxiety that in many patients worsens irritable bowel symptoms.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Clidinium family
Active ingredientClidinium BromideCat. No. P-C192-001CAS 3485-62-9
Pharmacopoeial impurityClidinium Bromide USP Related Compound ACat. No. P-C192-002CAS 2096336-00-2
Isotopically labelledClidinium Bromide-d10Cat. No. P-C192-003
ImpurityClidinium Impurity 1Cat. No. P-C192-006Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.