Active ingredientPerampanelCat. No. P-P058-001CAS 380917-97-5
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Impurity or related compound · Perampanel family
Pharmaceutical analytical standard4-(1,3,2-Dioxaborinan-2-yl)benzonitrile
Synonyms: Pyronoprene Impurity 2, Benzonitrile, 4-(1,3,2-dioxaborinan-2-yl)-
- Cat. No.
- P-P058-010
- CAS
- 152846-62-3
- Alternative CAS
- N/A
- Formula
- C10H10BNO2
- Molecular weight
- 187.00 g/mol
- Category
- Impurity or related compound
Family: Perampanel
An antiepileptic approved in 2012 in Europe and the United States for focal seizures and, later, also for primary generalised tonic-clonic seizures, as add-on treatment.
Did you know?It was the first antiepileptic in the class of selective non-competitive antagonists of AMPA receptors, which respond to glutamate, the brain's main excitatory neurotransmitter.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Perampanel family
Active ingredientPerampanelCat. No. P-P058-001CAS 380917-97-5
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ImpurityPerampanel Impurity 1Cat. No. P-P058-003CAS 380918-51-4
Impurity2-(1,3,2-Dioxaborinan-2-yl)benzamideCat. No. P-P058-004CAS 2377611-18-0
Impurity2-(1,3,2-Dioxaborinan-2-yl)benzonitrileCat. No. P-P058-005CAS 172732-52-4
Impurity2-(2-cyanophenyl)benzonitrileCat. No. P-P058-006CAS 4341-02-0
Impurity3-(1,3,2-Dioxaborinan-2-yl)benzonitrileCat. No. P-P058-007CAS 684648-40-6
ImpurityPerampanel Impurity 2Cat. No. P-P058-008CAS 380918-53-6Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.