Active ingredientCeftaroline Fosamil AcetateCat. No. P-C099-004CAS 400827-46-5
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Impurity or related compound · Ceftaroline family
Pharmaceutical analytical standard4-(1-Methylpyridin-1-ium-4-yl)thiazole-2-thiolate
Synonyms: Ceftaroline Fosamil Impurity 17, 4-(1-methylpyridin-1-ium-4-yl)-1,3-thiazole-2-thiolate, Ceftaroline Fosamil Impurity E
- Cat. No.
- P-C099-003
- CAS
- 1427207-46-2
- Alternative CAS
- 1427207-49-5 (hydrobromide)
- 1427207-56-4 (hydrochloride)
- 1427207-52-0 (alternative CAS, same compound)
- Formula
- C9H8N2S2
- Molecular weight
- 208.30 g/mol
- Category
- Impurity or related compound
Family: Ceftaroline
A fifth-generation cephalosporin also active against meticillin-resistant Staphylococcus aureus (MRSA), approved in the United States in 2010 for skin infections and community-acquired pneumonia.
Did you know?Against MRSA it works in pairs: a first molecule binds an allosteric site on PBP2a, the protein behind MRSA's resistance to other beta-lactams, opening its active site to a second molecule.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Ceftaroline family
Active ingredientCeftaroline Fosamil AcetateCat. No. P-C099-004CAS 400827-46-5
ImpurityCeftaroline Fosamil Di-phosphonateCat. No. P-C099-005CAS 1286218-64-1
ImpurityCeftaroline Fosamil ImpurityCat. No. P-C099-006CAS 1286218-63-0
ImpurityCeftaroline Impurity 1Cat. No. P-C099-007CAS 1277090-03-5
ImpurityCeftaroline Impurity 2Cat. No. P-C099-008CAS 1240196-56-8
ImpurityCeftaroline Impurity 3Cat. No. P-C099-009
ImpurityCeftaroline Impurity 4Cat. No. P-C099-010
ImpurityCeftaroline Impurity 5Cat. No. P-C099-012Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.