Active ingredientEplerenoneCat. No. P-E070-001CAS 107724-20-9
Drag to rotate
Impurity or related compound · Eplerenone family
Pharmaceutical analytical standard4,5alpha-Epoxy Eplerenone
Synonyms: Eplerenone 4,5-Epoxy analog
- Cat. No.
- P-E070-013
- CAS
- 209253-73-6
- Alternative CAS
- N/A
- Formula
- C24H30O7
- Molecular weight
- 430.50 g/mol
- Category
- Impurity or related compound
Family: Eplerenone
A selective mineralocorticoid receptor antagonist that blocks the action of aldosterone, approved in the United States in 2002 for hypertension and later also for heart failure after a heart attack.
Did you know?It was developed as a more selective version of spironolactone: unlike the older drug, it has very little affinity for androgen, progesterone and glucocorticoid receptors.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Eplerenone family
Active ingredientEplerenoneCat. No. P-E070-001CAS 107724-20-9
Pharmacopoeial impurityEplerenone EP Impurity ACat. No. P-E070-002CAS 209253-67-8
Pharmacopoeial impurityEplerenone EP Impurity BCat. No. P-E070-003CAS 192704-82-8
Pharmacopoeial impurityEplerenone EP Impurity CCat. No. P-E070-004CAS 95716-70-4
Pharmacopoeial impurityEplerenone EP Impurity DCat. No. P-E070-005CAS 209253-82-7
Pharmacopoeial impurityEplerenone EP Impurity ECat. No. P-E070-006CAS 209253-81-6
Pharmacopoeial impurityEplerenone EP Impurity F Sodium SaltCat. No. P-E070-007CAS 3070439-21-0
Pharmacopoeial impurityEplerenone EP Impurity GCat. No. P-E070-008CAS 41020-65-9Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.