Active ingredientOxonic Acid Potassium SaltCat. No. P-O065-001CAS 2207-75-2
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Impurity or related compound · Oxonic Acid family
Pharmaceutical analytical standard4-amino-1H-imidazole-2,5-dione
Synonyms: Oxonic Acid Impurity 1, 5-aminoimidazole-2,4-dione, Iminohydantoin
- Cat. No.
- P-O065-004
- CAS
- 60301-55-5
- Alternative CAS
- N/A
- Formula
- C3H3N3O2
- Molecular weight
- 113.08 g/mol
- Category
- Impurity or related compound
Family: Oxonic Acid
A triazine derivative that inhibits certain metabolic enzymes. As its potassium salt (oteracil) it is part of an oral anticancer combination with tegafur and gimeracil, approved in Europe in 2011, in which it stays in the gut and reduces side effects.
Did you know?It blocks uricase, the enzyme that breaks down uric acid in most other mammals but is missing in humans: that is why researchers give it to mice and rats to study gout in the laboratory.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Oxonic Acid family
Active ingredientOxonic Acid Potassium SaltCat. No. P-O065-001CAS 2207-75-2
Impurity1,3,5-triazine-2,4(1H,3H)-dioneCat. No. P-O065-003CAS 71-33-0Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.