Active ingredientBenzocaineCat. No. P-B043-001CAS 94-09-7
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Pharmacopoeial impurity · Benzocaine family
Pharmaceutical analytical standard4-Aminobenzoic Acid
Synonyms: p-aminobenzoic acid, PABA, Vitamin BX, p-Carboxyaniline, Para-aminobenzoic acid, Sunbrella, Pabacyd, Paraminol, Amben, Benzoic acid, 4-amino-, p-Carboxyphenylamine, Pabafilm, Pabamine, Paranate, Romavit, Vitamin H', Bacterial vitamin H1, Anticanitic vitamin, Chromotrichia factor, RVPaba Lipstick, Trichochromogenic factor, Papacidum, Rvpaba, Anti-chromotrichia factor, Benzoic acid, p-amino-, gamma-Aminobenzoic acid, Aminobenzoic acid, Paraminan, Hachemina, Pabagel, Pabanol, Caswell No. 033B, Kyselina p-aminobenzoova, Vitamin H1, Actipol, Aniline-4-carboxylic acid, Anticantic vitamin, NSC 7627, EPA Pesticide Chemical Code 233300, Aminobenzoic acid, para, Aminobenzoate, p-aminobezoic acid, gamma-Aminobenzoate, Trochromogenic factor, Aniline-4-carboxylate, p-amino-benzoate, Aminobenzoic Acid, USP, H-(4)Abz-OH, p-Aminobenzenecarboxylic acid, Benzocaine EP Impurity G
- Cat. No.
- P-B043-009
- CAS
- 150-13-0
- Alternative CAS
- 206557-08-6 (sodium salt hydrate)
- 22669-27-8 (hydrochloride)
- 555-06-6 (sodium salt)
- 54287-22-8 (sodium salt)
- 60154-17-8 (calcium salt)
- 14926-08-0 (magnesium salt)
- 203308-44-5 (hydrate)
- 16090-06-5 (lithium salt)
- 138-84-1 (potassium salt)
- 25136-77-0 (alternative CAS, same compound)
- 2906-28-7 (alternative CAS, same compound)
- Formula
- C7H7NO2
- Molecular weight
- 137.14 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Benzocaine
An ester-type local anaesthetic, synthesised in 1890 in Eberbach by German chemist Eduard Ritsert and on the market since 1902. Poorly soluble in water, it is used on the skin and mucous membranes: sore throats, mouth ulcers, toothache, sunburn.
Did you know?It is not only for humans: dissolved in a water bath, it is commonly used to anaesthetise amphibians, such as frogs and salamanders, before surgery.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- 4-Aminobenzoic acid CRSEP Y0000173
More products in the Benzocaine family
Active ingredientBenzocaineCat. No. P-B043-001CAS 94-09-7
Pharmacopoeial impurityBenzocaine EP Impurity ACat. No. P-B043-002CAS 623-04-1
Pharmacopoeial impurityBenzocaine EP Impurity CCat. No. P-B043-003CAS 582-33-2
Pharmacopoeial impurityBenzocaine EP Impurity DCat. No. P-B043-005CAS 87-25-2
Pharmacopoeial impurityBenzocaine EP Impurity FCat. No. P-B043-006CAS 1877-77-6
Isotopically labelledBenzocaine-d4Cat. No. P-B043-007CAS 342611-08-9
NitrosamineEthyl 4-(methylnitrosoamino)benzoateCat. No. P-B043-008CAS 208176-48-1
Pharmacopoeial impurity4-Nitrobenzoic AcidCat. No. P-B043-010CAS 62-23-7Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.