Active ingredientTizanidineCat. No. P-T138-001CAS 51322-75-9
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Impurity or related compound · Tizanidine family
Pharmaceutical analytical standard5-Amino-6-chloro-2,1,3-benzothiadiazole
Synonyms: Tizanidine Impurity 5, 5-chloro-2,1,3-benzothiadiazol-6-amine
- Cat. No.
- P-T138-016
- CAS
- 100191-31-9
- Alternative CAS
- N/A
- Formula
- C6H4ClN3S
- Molecular weight
- 185.63 g/mol
- Category
- Impurity or related compound
Family: Tizanidine
A centrally acting muscle relaxant and alpha-2 adrenergic agonist that reduces muscle spasticity caused by multiple sclerosis, spinal cord injury or cerebral palsy. Its synthesis was first published in 1974, and it has been approved in the United States since 1996.
Did you know?It is a close chemical relative of clonidine, a blood pressure medicine: both act on alpha-2 receptors, but tizanidine is at least ten times weaker at lowering blood pressure.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Tizanidine family
Active ingredientTizanidineCat. No. P-T138-001CAS 51322-75-9
Active ingredientTizanidine HydrochlorideCat. No. P-T138-002CAS 64461-82-1
Pharmacopoeial impurityTizanidine EP Impurity ACat. No. P-T138-003CAS 51322-69-1
Pharmacopoeial impurityTizanidine EP Impurity CCat. No. P-T138-004CAS 1147548-83-1
Pharmacopoeial impurityTizanidine EP Impurity D HydroiodideCat. No. P-T138-005CAS 51323-03-6
Pharmacopoeial impurityTizanidine EP Impurity ECat. No. P-T138-006CAS 30536-19-7
Pharmacopoeial impurityTizanidine EP Impurity FCat. No. P-T138-007CAS 1147548-85-3
Pharmacopoeial impurityTizanidine EP Impurity GCat. No. P-T138-008CAS 51322-80-6Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.