Active ingredientZidovudineCat. No. P-Z015-001CAS 30516-87-1
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Impurity or related compound · Zidovudine family
Pharmaceutical analytical standard5-O-Tritylthymidine
Synonyms: Monotritylthymidine, Trt-dT
- Cat. No.
- P-Z015-018
- CAS
- 7791-71-1
- Alternative CAS
- N/A
- Formula
- C29H28N2O5
- Molecular weight
- 484.55 g/mol
- Category
- Impurity or related compound
Family: Zidovudine
A thymidine analogue that inhibits HIV reverse transcriptase. Approved in the United States in March 1987, it was the first medicine against HIV and AIDS; it is also used to reduce transmission of the virus from mother to child during pregnancy and birth.
Did you know?It was synthesised in 1964 in Detroit by the chemist Jerome Horwitz as a possible cancer drug: it proved ineffective and was almost forgotten for twenty years, until its activity against HIV was discovered.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Zidovudine family
Active ingredientZidovudineCat. No. P-Z015-001CAS 30516-87-1
Pharmacopoeial impurityZidovudine EP Impurity BCat. No. P-Z015-003CAS 25526-94-7
Pharmacopoeial impurityZidovudine EP Impurity CCat. No. P-Z015-004CAS 65-71-4
Pharmacopoeial impurityZidovudine EP Impurity KCat. No. P-Z015-005CAS 596-31-6
Pharmacopoeial impurityZidovudine USP Impurity GCat. No. P-Z015-006CAS 148665-49-0
MetaboliteZidovudine Glucuronide Sodium SaltCat. No. P-Z015-007CAS 133525-01-6
ImpurityZidovudine Impurity FCat. No. P-Z015-013CAS 16053-52-4
Impurity3'-ent-ZidovudineCat. No. P-Z015-015CAS 73971-82-1Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.