Active ingredientIsoprenalineCat. No. P-I090-001CAS 7683-59-2
Drag to rotate
Impurity or related compound · Isoprenaline family
Pharmaceutical analytical standard6,7-Dihydroxy-1-isopropylindolin-3-one
Synonyms: 6,7-dihydroxy-1-propan-2-yl-2H-indol-3-one, Isoproterenol Impurity 8
- Cat. No.
- P-I090-012
- CAS
- 2512214-03-6
- Alternative CAS
- N/A
- Formula
- C11H13NO3
- Molecular weight
- 207.23 g/mol
- Category
- Impurity or related compound
Family: Isoprenaline
The first selective beta-adrenergic receptor agonist, discovered in 1940 and approved in the United States in 1947: once used for asthma, today it is given in emergencies for slow heart rate and heart block.
Did you know?In 1948 Raymond Ahlquist noticed that isoprenaline was the most potent agent on the heart and the weakest at constricting blood vessels: from this he proposed two receptor types, alpha and beta. His paper was at first rejected.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Isoprenaline family
Active ingredientIsoprenalineCat. No. P-I090-001CAS 7683-59-2
Active ingredientIsoprenaline HydrochlorideCat. No. P-I090-002CAS 51-30-9
Active ingredientIsoprenaline Sulfate DihydrateCat. No. P-I090-003CAS 6078-56-4
Pharmacopoeial impurityIsoprenaline EP Impurity A HClCat. No. P-I090-004CAS 16899-81-3
Isotopically labelledIsoproterenol-d7 HClCat. No. P-I090-005
NitrosamineN-Nitroso Isoprenaline EP Impurity ACat. No. P-I090-006
NitrosamineN-Nitroso IsoproterenolCat. No. P-I090-007
Impurity1-Isopropyl-1H-indole-3,5,6-triolCat. No. P-I090-008CAS 73853-05-1Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.