Active ingredientTadalafilCat. No. P-T005-001CAS 171596-29-5
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Impurity or related compound · Tadalafil family
Pharmaceutical analytical standard(6R,12aS)-N-Desmethyl Tadalafil
Synonyms: (6R,12aS)-N-Desmethyl ent-Tadalafil, Tadalafil EP Impurity A N-Desmethyl Impurity
- Cat. No.
- P-T005-025
- CAS
- 929100-66-3
- Alternative CAS
- 171488-04-3 (alternative CAS, same compound)
- Formula
- C21H17N3O4
- Molecular weight
- 375.38 g/mol
- Category
- Impurity or related compound
Family: Tadalafil
A phosphodiesterase-5 inhibitor on the market since 2003 for erectile dysfunction, and later for benign prostatic hyperplasia and pulmonary hypertension.
Did you know?It lasts much longer than its rivals, up to 36 hours: that is why it was nicknamed "the weekend pill".
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Tadalafil family
Active ingredientTadalafilCat. No. P-T005-001CAS 171596-29-5
Pharmacopoeial impurityTadalafil EP Impurity ACat. No. P-T005-002CAS 171596-27-3
Pharmacopoeial impurityTadalafil EP Impurity BCat. No. P-T005-003CAS 629652-72-8
Pharmacopoeial impurityTadalafil EP Impurity CCat. No. P-T005-004CAS 171596-28-4
Pharmacopoeial impurityTadalafil EP Impurity ECat. No. P-T005-005CAS 2520114-41-2
Pharmacopoeial impurityTadalafil EP Impurity GCat. No. P-T005-006CAS 2520114-46-7
Pharmacopoeial impurityTadalafil EP Impurity HCat. No. P-T005-007CAS 1978322-98-3
Pharmacopoeial impurityTadalafil EP Impurity I (Mixture of Diastereomers)Cat. No. P-T005-008CAS 2378614-29-8Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.