Active ingredientClobazamCat. No. P-C197-001CAS 22316-47-8
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Impurity or related compound · Clobazam family
Pharmaceutical analytical standard7-Deschloro-8-chloro Clobazam
Synonyms: 7-chloro-5-methyl-1-phenyl-1,5-benzodiazepine-2,4-dione
- Cat. No.
- P-C197-018
- CAS
- 22316-27-4
- Alternative CAS
- N/A
- Formula
- C16H13ClN2O2
- Molecular weight
- 300.74 g/mol
- Category
- Impurity or related compound
Family: Clobazam
A benzodiazepine synthesised in 1966 in Milan, approved from 1970 as an anxiolytic and later also used for epilepsy; it reached the United States in 2011 for Lennox-Gastaut syndrome.
Did you know?It is the only 1,5-benzodiazepine to enter clinical use: the two nitrogen atoms in its ring sit at positions 1 and 5, instead of the classic positions 1 and 4.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Clobazam family
Active ingredientClobazamCat. No. P-C197-001CAS 22316-47-8
Pharmacopoeial impurityClobazam EP Impurity ACat. No. P-C197-002CAS 22316-55-8
Pharmacopoeial impurityClobazam EP Impurity BCat. No. P-C197-003CAS 22316-24-1
Pharmacopoeial impurityClobazam EP Impurity CCat. No. P-C197-004CAS 22316-16-1
Pharmacopoeial impurityClobazam EP Impurity DCat. No. P-C197-005CAS 2092997-47-0
Pharmacopoeial impurityClobazam EP Impurity ECat. No. P-C197-006CAS 75524-13-9
Pharmacopoeial impurityClobazam EP Impurity FCat. No. P-C197-007CAS 2089061-92-5
Pharmacopoeial impurityClobazam USP Related Compound GCat. No. P-C197-008CAS 75524-10-6Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.