Active ingredientEtodolacCat. No. P-E133-001CAS 41340-25-4
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Impurity or related compound · Etodolac family
Pharmaceutical analytical standard8-(1-Hydroxyethyl) Etodolac
Synonyms: Pyrano(3,4-b)indole-1-acetic acid, 1,3,4,9-tetrahydro-1-ethyl-8-(1-hydroxyethyl)-, Etodolac Impurity 15
- Cat. No.
- P-E133-031
- CAS
- 101901-08-0
- Alternative CAS
- N/A
- Formula
- C17H21NO4
- Molecular weight
- 303.36 g/mol
- Category
- Impurity or related compound
Family: Etodolac
A non-steroidal anti-inflammatory drug that acts preferentially on COX-2, patented in 1971, in clinical use since 1985 and approved in the United States in 1991: it is used for pain and inflammation in osteoarthritis and rheumatoid arthritis.
Did you know?The medicine is a mixture of two mirror-image forms: the R form does not act on cyclooxygenases, but in liver cancer cells it lowers levels of beta-catenin, a cell growth protein.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Etodolac family
Active ingredientEtodolacCat. No. P-E133-001CAS 41340-25-4
Pharmacopoeial impurityEtodolac EP Impurity ACat. No. P-E133-002CAS 41339-67-7
Pharmacopoeial impurityEtodolac EP Impurity BCat. No. P-E133-003CAS 41340-19-6
Pharmacopoeial impurityEtodolac EP Impurity CCat. No. P-E133-004CAS 109518-47-0
Pharmacopoeial impurityEtodolac EP Impurity DCat. No. P-E133-005CAS 57917-63-2
Pharmacopoeial impurityEtodolac EP Impurity ECat. No. P-E133-006CAS 57817-27-3
Pharmacopoeial impurityEtodolac EP Impurity FCat. No. P-E133-007CAS 849630-65-5
Pharmacopoeial impurityEtodolac EP Impurity GCat. No. P-E133-008CAS 57816-83-8Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.