Active ingredientAcetazolamideCat. No. P-A020-001CAS 59-66-5
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Impurity or related compound · Acetazolamide family
Pharmaceutical analytical standardAcetazolamide Impurity 1
Synonyms: (E)-N-(5-(benzylthio)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene) Acetamide, N-(5-benzylsulfanyl-3-methyl-1,3,4-thiadiazol-2-ylidene)acetamide, N-(3-Methyl-5-((phenylmethyl)thio)-1,3,4-thiadiazol-2(3H)-ylidene)acetamide, Acetamide, n-(3-methyl-5-((phenylmethyl)thio)-1,3,4-thiadiazol-2(3h)-ylidene)-
- Cat. No.
- P-A020-012
- CAS
- 95046-30-3
- Alternative CAS
- N/A
- Formula
- C12H13N3OS2
- Molecular weight
- 279.38 g/mol
- Category
- Impurity or related compound
Family: Acetazolamide
A carbonic anhydrase inhibitor created in the early 1950s and used against glaucoma since 1954; today it also serves for altitude sickness, some forms of epilepsy and idiopathic intracranial hypertension.
Did you know?Mountaineers taking it report that champagne and fizzy drinks taste odd: in 2009 it was found that sour-taste cells sense the bubbles through carbonic anhydrase.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Acetazolamide family
Active ingredientAcetazolamideCat. No. P-A020-001CAS 59-66-5
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Pharmacopoeial impurityAcetazolamide EP Impurity ECat. No. P-A020-006CAS 827026-60-8
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Pharmacopoeial impurityAcetazolamide EP Impurity GCat. No. P-A020-008CAS 2349-67-9Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.