Pharmacopoeial impurityAcetylcysteine EP Impurity ACat. No. P-A025-002CAS 56-89-3
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Active ingredient · Acetylcysteine family
Pharmaceutical analytical standardAcetylcysteine
Synonyms: N-Acetyl-L-Cysteine, Mercapturic acid, Acetadote, Fluimucetin, Respaire, Acetilcisteina, Brunac, N-Acetyl cysteine, Syntemucol, Tixair, Neo-fluimucil, L-Cysteine, N-acetyl-, Mucolyticum-Lappe, N-Acetyl-3-mercaptoalanine, Cysteine, N-acetyl-, L-, Mucolyticum, Cetylev, Mercapturic acid, (R)-, Mucosil-20, Fluatox, Fluimicil, Mucolator, Mucret, Muco sanigen, Oristar nalc, Mucosil-10, N-acetyi-l-cysteine, L-alpha-Acetamido-beta-mercaptopropionic acid, Mucocedyl, NSC 111180, Yournac, Bromuc, BronchoFips, Genac, Siran, Fluimucil long, MPectil, Fluimucil n, Respi-nac, Mucopect, Dampo, Sanigen, Muco, En-cys, Larylin NAC, Acid, Mercapturic, A-cys, NAC, Bisolvon, Tris-NAC, Fluimucil 600, Acetylcystein, mentopin, NAC AL, CorniSol Eye Wash Drops, Broncholysin, Mucomyst, Fluimucil, Parvolex, Airbron, Fluprowit, Mucosolvin, Flumucetin, Mucofilin, Mucosil, Fabrol, Inspir, Acetyl-L-cysteine, Fluimicil Infantil, Lysomucil, Acetein, Ac-Cys-OH, Mucolytikum Lappe, Exomuc, N-acetylcystein, NAC-TB, N-acetyl-L-cystein, N-acetyl-(R)-cysteine, Flumil, Ilube, AcCys, N-acetyl-l-cys, Ilube (eye drops), N-A-C Sustain, ac-l-cys-oh, N-Acetyl-L-cysteine (TF), Propanoic acid, 2-acetylamino-3-mercapto-
- Cat. No.
- P-A025-001
- CAS
- 616-91-1
- Alternative CAS
- 18829-79-3 (hydrochloride)
- 36330-79-7 (magnesium salt)
- 49793-39-7 (zinc salt)
- 19542-74-6 (sodium salt)
- 63664-54-0 (sodium salt)
- 213178-96-2 (lithium salt)
- 7546-23-8 (calcium salt)
- 1202024-59-6 (hydrobromide)
- Formula
- C5H9NO3S
- Molecular weight
- 163.19 g/mol
- Category
- Active ingredient (API)
The N-acetyl derivative of the amino acid cysteine, used as a mucolytic: it thins the thick, sticky mucus of the airways so that it can be cleared more easily.
Did you know?In microbiology, together with sodium hydroxide, it is used to liquefy sputum before culturing the tuberculosis bacillus (NALC-NaOH method), helping the mycobacteria in the sample to grow.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- AcetylcysteineBP 907
- Acetylcysteine CRSEP A0150000
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Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.