Active ingredientGuanfacineCat. No. P-G068-001CAS 29110-47-2
Drag to rotate
Impurity or related compound · Guanfacine family
Pharmaceutical analytical standardAD6F9U9Zwf Hydrochloride
Synonyms: Guanfacine Impurity 2 HCl, AD6F9U9Zwf, N-(Aminoiminomethyl)-2,4-dichlorobenzeneacetamide hydrochloride, Benzeneacetamide, N-(aminoiminomethyl)-2,4-dichloro-, monohydrochloride
- Cat. No.
- P-G068-013
- CAS
- 64647-47-8
- Alternative CAS
- 57486-50-7 (free base)
- Formula
- C9H9Cl2N3O·HCl
- Molecular weight
- 282.55 g/mol
- Category
- Impurity or related compound
Family: Guanfacine
An agonist of alpha-2A adrenergic receptors in the brain, approved in the United States in 1986 for hypertension and, since the late 2000s, as an extended-release form for attention deficit hyperactivity disorder (ADHD).
Did you know?Its use for disorders of the prefrontal cortex, such as ADHD, grew out of research by Amy Arnsten's laboratory at Yale University; it is not a stimulant.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Guanfacine family
Active ingredientGuanfacineCat. No. P-G068-001CAS 29110-47-2
Active ingredientGuanfacine HydrochlorideCat. No. P-G068-002CAS 29110-48-3
Metabolite3-Hydroxy Guanfacine GlucuronideCat. No. P-G068-003
Isotopically labelledGuanfacine-13C-15N3Cat. No. P-G068-004CAS 1189924-28-4
Isotopically labelledN1-Nitroso Guanfacine-13C-15N3Cat. No. P-G068-005
Isotopically labelledN2-Nitroso Guanfacine-13C-15N3Cat. No. P-G068-006
NitrosamineN1-Nitroso GuanfacineCat. No. P-G068-007
NitrosamineN2-Nitroso GuanfacineCat. No. P-G068-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.