Active ingredientAdapaleneCat. No. P-A037-001CAS 106685-40-9
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Impurity or related compound · Adapalene family
Pharmaceutical analytical standardAdapalene Impurity 2
Synonyms: 1-(2-Methoxy-5-naphthalen-2-ylphenyl)adamantane
- Cat. No.
- P-A037-021
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C27H28O
- Molecular weight
- 368.52 g/mol
- Category
- Impurity or related compound
Family: Adapalene
A synthetic third-generation retinoid, a naphthoic acid derivative, born from dermatological research in France and approved in the United States in 1996 for acne.
Did you know?In 2016 it became, in the United States, the first new active ingredient for acne sold without a prescription in more than thirty years.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Adapalene family
Active ingredientAdapaleneCat. No. P-A037-001CAS 106685-40-9
Pharmacopoeial impurityAdapalene EP Impurity ACat. No. P-A037-002CAS 932033-58-4
Pharmacopoeial impurityAdapalene EP Impurity BCat. No. P-A037-003CAS 1346599-76-5
Pharmacopoeial impurityAdapalene EP Impurity CCat. No. P-A037-004CAS 43109-77-9
Pharmacopoeial impurityAdapalene EP Impurity DCat. No. P-A037-005CAS 932033-57-3
Pharmacopoeial impurityAdapalene USP Related Compound ACat. No. P-A037-006CAS 33626-98-1
Pharmacopoeial impurityAdapalene USP Related Compound BCat. No. P-A037-007CAS 106685-41-0
MetaboliteAdapalene Acyl-GlucuronideCat. No. P-A037-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.