Active ingredientAlfacalcidolCat. No. P-A072-001CAS 41294-56-8
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Impurity or related compound · Alfacalcidol family
Pharmaceutical analytical standardAlfacalcidol Impurity 5
- Cat. No.
- P-A072-011
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C27H44O3
- Molecular weight
- 416.65 g/mol
- Category
- Impurity or related compound
Family: Alfacalcidol
A synthetic vitamin D analogue (1-alpha-hydroxycholecalciferol), synthesised in the early 1970s and in use since 1978 for bone and calcium disorders in chronic kidney disease.
Did you know?It already carries the 1-alpha-hydroxyl group and is converted in the liver into calcitriol, the active form of vitamin D: this is why it works even when the kidneys can no longer activate vitamin D.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Alfacalcidol family
Active ingredientAlfacalcidolCat. No. P-A072-001CAS 41294-56-8
Pharmacopoeial impurityAlfacalcidol EP Impurity ACat. No. P-A072-002CAS 65445-14-9
Pharmacopoeial impurityAlfacalcidol EP Impurity BCat. No. P-A072-003CAS 63181-13-5
Pharmacopoeial impurityAlfacalcidol EP Impurity CCat. No. P-A072-004CAS 82266-85-1
Isotopically labelledAlfacalcidol-d7Cat. No. P-A072-005
Impurity1-Hydroxyprevitamin D3Cat. No. P-A072-006CAS 41461-13-6
ImpurityAlfacalcidol Impurity 1Cat. No. P-A072-007CAS 104651-70-9
ImpurityAlfacalcidol Impurity 2Cat. No. P-A072-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.