Active ingredientAlfuzosin HClCat. No. P-A074-001CAS 81403-68-1
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Pharmacopoeial impurity · Alfuzosin family
Pharmaceutical analytical standardAlfuzosin EP Impurity F
Synonyms: 6,7-dimethoxy-2-N,2-N-dimethylquinazoline-2,4-diamine, NSC 403405, Alfuzosin Impurity F
- Cat. No.
- P-A074-006
- CAS
- 19216-53-6
- Alternative CAS
- 19216-68-3 (hydrochloride)
- Formula
- C12H16N4O2
- Molecular weight
- 248.29 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Alfuzosin
An alpha-1 blocker patented in 1979 and approved in 1988 (in the United States in 2003): it relaxes the muscle of the prostate and urethra and eases the urinary symptoms of benign prostatic hyperplasia.
Did you know?In the early 1980s it was developed as a blood pressure drug. Curiously, it does not shrink the prostate: it acts only on smooth muscle, so urine flows more easily.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Alfuzosin family
Active ingredientAlfuzosin HClCat. No. P-A074-001CAS 81403-68-1
Pharmacopoeial impurityAlfuzosin EP Impurity ACat. No. P-A074-002CAS 98902-36-4
Pharmacopoeial impurityAlfuzosin EP Impurity CCat. No. P-A074-003CAS 98902-34-2
Pharmacopoeial impurityAlfuzosin EP Impurity DCat. No. P-A074-004CAS 76362-29-3
Pharmacopoeial impurityAlfuzosin EP Impurity E HClCat. No. P-A074-005CAS 1796934-51-4
Isotopically labelledAlfuzosin-13C-d3Cat. No. P-A074-007
Isotopically labelledAlfuzosin-d3Cat. No. P-A074-008CAS 1006724-55-5
ImpurityAlfuzosin hydrochloride Impurity GCat. No. P-A074-009CAS 928780-95-4Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.