Pharmacopoeial impurityAllopurinol EP Impurity A SulfateCat. No. P-A082-002CAS 27511-79-1
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Active ingredient · Allopurinol family
Pharmaceutical analytical standardAllopurinol
Synonyms: 1,5-dihydropyrazolo[5,4-d]pyrimidin-4-one, Zyloric, Takanarumin, Suspendol, Allopur, Bloxanth, Uriprim, Xanturat, Urbol, Ketobun-A, Nektrohan, Adenock, Aluline, Dabrosin, Urobenyl, Alopurinol, NSC 1390, Sigapurol, Uricto, Xanthomax-100, Xanthomax-300, NSC 101655, Aluline 100, Aluline 300, Hamarin 100, Hamarin 300, Zyloric-300, Milurite, Allohexan, Pan Quimica, Zurinol, Zyloprim, Lopurin, Urosin, Atisuril, Epidropal, Uricemil, Anzief, Urolit, Anoprolin, Miniplanor, Ailural, Allozym, Alositol, Cosuric, Gichtex, Ledopur, Progout, Aloral, Apurol, Riball, Ketanrift, Monarch, Hexanuret, Epuric, Dura Al, Uritas, Ailurial, Allohexal, Pharmakon1600-01500108, NSC 755858
- Cat. No.
- P-A082-001
- CAS
- 315-30-0
- Alternative CAS
- 180749-06-8 (alternative CAS, same compound)
- 180749-08-0 (alternative CAS, same compound)
- 73334-58-4 (alternative CAS, same compound)
- 180749-09-1 (alternative CAS, same compound)
- 916980-04-6 (alternative CAS, same compound)
- 180749-07-9 (alternative CAS, same compound)
- 184789-03-5 (alternative CAS, same compound)
- 291279-53-3 (alternative CAS, same compound)
- Formula
- C5H4N4O
- Molecular weight
- 136.11 g/mol
- Category
- Active ingredient (API)
A xanthine oxidase inhibitor that reduces the production of uric acid, developed in the United States by Gertrude Elion and George Hitchings and used against gout since the mid-1960s.
Did you know?It was first studied for another purpose: protecting the anti-leukaemia drug 6-mercaptopurine from being broken down. Elion and Hitchings later received the 1988 Nobel Prize in Medicine.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- AllopurinolBP 870
- Allopurinol CRSEP A0350000
More products in the Allopurinol family
Pharmacopoeial impurityAllopurinol EP Impurity A SulfateCat. No. P-A082-002CAS 27511-79-1
Pharmacopoeial impurityAllopurinol EP Impurity ACat. No. P-A082-003CAS 5334-31-6
Pharmacopoeial impurityAllopurinol EP Impurity BCat. No. P-A082-004CAS 22407-20-1
Pharmacopoeial impurityAllopurinol EP Impurity CCat. No. P-A082-005CAS 1346604-13-4
Pharmacopoeial impurityAllopurinol EP Impurity DCat. No. P-A082-006CAS 6994-25-8
Pharmacopoeial impurityAllopurinol EP Impurity ECat. No. P-A082-007CAS 31055-19-3
Pharmacopoeial impurityAllopurinol USP Related Compound FCat. No. P-A082-008CAS 321571-07-7
Isotopically labelledAllopurinol-d2Cat. No. P-A082-010CAS 916979-34-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.