Active ingredientAlosetron HClCat. No. P-A091-001CAS 122852-69-1
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Metabolite · Alosetron family
Pharmaceutical analytical standardAlosetron N-Glucuronide
- Cat. No.
- P-A091-002
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C23H26N4O7
- Molecular weight
- 470.48 g/mol
- Category
- Metabolite
Family: Alosetron
A serotonin 5-HT3 receptor antagonist that slows transit through the colon, approved in the United States in 2000 for severe diarrhoea-predominant irritable bowel syndrome in women.
Did you know?It is a 'relative' of ondansetron, used against nausea, but its target is the gut: it acts on 5-HT3 receptors of the enteric nervous system, the dense network of neurons that runs the gut.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Alosetron family
Active ingredientAlosetron HClCat. No. P-A091-001CAS 122852-69-1
Isotopically labelledAlosetron-13C-d3Cat. No. P-A091-003
Isotopically labelledAlosetron-d3Cat. No. P-A091-004CAS 1189919-71-8
NitrosamineN-Nitroso AlosetronCat. No. P-A091-005
Impurity3,4-Didehydro AlosetronCat. No. P-A091-006CAS 122852-86-2
Impurity4-Hydroxy AlosetronCat. No. P-A091-007
Impurity4-MethylimidazoleCat. No. P-A091-008CAS 822-36-6
Impurity6-Hydroxy Alosetron HClCat. No. P-A091-009Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.