Active ingredientAlverine CitrateCat. No. P-A100-001CAS 5560-59-8
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Pharmacopoeial impurity · Alverine family
Pharmaceutical analytical standardAlverine EP Impurity A
Synonyms: Alverine Citrate EP Impurity A (1-Chloro-3-phenylpropane), 3-chloropropylbenzene, Benzene, (3-chloropropyl)-, gamma-Chloropropylbenzene, Benzene, (chloropropyl)-, gamma-Chloropro, Alverine Impurity A, Alverine Imp. A
- Cat. No.
- P-A100-004
- CAS
- 104-52-9
- Alternative CAS
- N/A
- Formula
- C9H11Cl
- Molecular weight
- 154.64 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Alverine
An antispasmodic that directly relaxes the smooth muscle of the gut and uterus, first described in 1939: it is used for irritable bowel syndrome, diverticular disease and painful periods.
Did you know?Besides relieving muscle spasm it blocks serotonin 5-HT1A receptors, reducing the rectal hypersensitivity to pain typical of irritable bowel syndrome.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Alverine family
Active ingredientAlverine CitrateCat. No. P-A100-001CAS 5560-59-8
Pharmacopoeial impurityAlverine Citrate EP Impurity CCat. No. P-A100-002CAS 13125-63-8
Pharmacopoeial impurityAlverine Citrate EP Impurity DCat. No. P-A100-003CAS 2732347-31-6
Pharmacopoeial impurityAlverine EP Impurity BCat. No. P-A100-005CAS 122-97-4
Pharmacopoeial impurityAlverine EP Impurity E HClCat. No. P-A100-006CAS 878784-75-9
Metabolite4-Hydroxy Alverine GlucuronideCat. No. P-A100-007
Isotopically labelled4-Hydroxy Alverine-d5 HClCat. No. P-A100-008
Isotopically labelledAlverine-d5 CitrateCat. No. P-A100-009CAS 1215327-00-6Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.