Active ingredientAmidotrizoic AcidCat. No. P-A114-001CAS 117-96-4
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Active ingredient · Amidotrizoic Acid family
Pharmaceutical analytical standardAmidotrizoic Acid Dihydrate
Synonyms: Diatrizoic acid dihydrate, Benzoic acid, 3,5-bis(acetylamino)-2,4,6-triiodo-, dihydrate, Amidotrizoic acid RS, Diatrizoic acid dihydrate, suitable for Hematology & Histology
- Cat. No.
- P-A114-006
- CAS
- 50978-11-5
- Alternative CAS
- N/A
- Formula
- C11H9I3N2O4·2H2O
- Molecular weight
- 649.94 g/mol
- Category
- Active ingredient (API)
Family: Amidotrizoic Acid
An ionic iodinated X-ray contrast agent, approved in the United States in 1954 and used to image veins, the urinary tract, joints and, by mouth or rectally, the digestive tract; it is on the WHO List of Essential Medicines.
Did you know?Besides imaging, it is used in newborns with meconium ileus: by drawing water into the bowel it loosens the thick, sticky meconium that blocks it.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Amidotrizoic acid dihydrate CRSEP A0365000
More products in the Amidotrizoic Acid family
Active ingredientAmidotrizoic AcidCat. No. P-A114-001CAS 117-96-4
Pharmacopoeial impurityAmidotrizoic Acid EP Impurity BCat. No. P-A114-002CAS 162193-52-4
Pharmacopoeial impurityAmidotrizoic Acid EP Impurity DCat. No. P-A114-003
Isotopically labelledAmidotrizoic Acid-d6Cat. No. P-A114-004CAS 1189668-69-6
Active ingredientSodium AmidotrizoateCat. No. P-A114-005CAS 737-31-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.