Active ingredientAmiodarone HydrochlorideCat. No. P-A130-002CAS 19774-82-4
Drag to rotate
Active ingredient · Amiodarone family
Pharmaceutical analytical standardAmiodarone
Synonyms: Atlansil, Methanone, (2-butyl-3-benzofuranyl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)-, Kordaron, Amiodarex, Cordarone, Amjodaronum, Ketone, 2-butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl, Amidorone, Aratac
- Cat. No.
- P-A130-001
- CAS
- 1951-25-3
- Alternative CAS
- 19774-82-4 (hydrochloride)
- 135048-43-0 (alternative CAS, same compound)
- Formula
- C25H29I2NO3
- Molecular weight
- 645.32 g/mol
- Category
- Active ingredient (API)
A class III antiarrhythmic synthesised in Belgium in 1961 by the chemists Tondeur and Binon and first used against angina; since the 1970s it has been used for ventricular and supraventricular arrhythmias. More than a third of its weight is iodine.
Did you know?It descends from khellin, the active principle of the plant Ammi visnaga, whose fruits are mentioned in Egyptian papyri against renal colic and angina; cromoglicate, used in asthma and allergies, also derives from khellin.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Amiodarone family
Active ingredientAmiodarone HydrochlorideCat. No. P-A130-002CAS 19774-82-4
Pharmacopoeial impurityAmiodarone EP Impurity G HydrochlorideCat. No. P-A130-003
Pharmacopoeial impurityAmiodarone EP Impurity ACat. No. P-A130-004CAS 23551-25-9
Pharmacopoeial impurityAmiodarone EP Impurity A OxalateCat. No. P-A130-005CAS 2984442-50-2
Pharmacopoeial impurityAmiodarone EP Impurity A HClCat. No. P-A130-006CAS 95820-13-6
Pharmacopoeial impurityAmiodarone EP Impurity B HydrochlorideCat. No. P-A130-007CAS 96027-74-6
Pharmacopoeial impurityAmiodarone EP Impurity C HydrochlorideCat. No. P-A130-008CAS 1397201-93-2
Pharmacopoeial impurityAmiodarone EP Impurity CCat. No. P-A130-009CAS 85642-08-6Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.