Active ingredientAmrubicinCat. No. P-A148-001CAS 110267-81-7
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Impurity or related compound · Amrubicin family
Pharmaceutical analytical standardAmrubicinol
- Cat. No.
- P-A148-003
- CAS
- 186353-53-7
- Alternative CAS
- N/A
- Formula
- C25H27NO9
- Molecular weight
- 485.49 g/mol
- Category
- Impurity or related compound
Family: Amrubicin
An anthracycline that blocks the enzyme topoisomerase II, used against lung cancer, particularly small cell lung cancer; it was first marketed in Japan in 2002.
Did you know?It was the first anthracycline made by de novo synthesis, described in 1989: the first anthracyclines, such as daunorubicin discovered in Italy in the early 1960s, were instead extracted from the bacterium Streptomyces peucetius.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Amrubicin family
Active ingredientAmrubicinCat. No. P-A148-001CAS 110267-81-7
Active ingredientAmrubicin HClCat. No. P-A148-002CAS 110311-30-3Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.