Isotopically labelledAnnamycin-d3Cat. No. P-A166-002
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Active ingredient · Annamycin family
Pharmaceutical analytical standardAnnamycin
Synonyms: Naxtarubicin, Naxtarubicina, Naxtarubicine
- Cat. No.
- P-A166-001
- CAS
- 92689-49-1
- Alternative CAS
- N/A
- Formula
- C26H25IO11
- Molecular weight
- 640.38 g/mol
- Category
- Active ingredient (API)
A synthetic anthracycline described in the 1990s, designed to be less toxic to the heart and to get around multidrug resistance; in liposomal form it has been studied for acute myeloid leukaemia and for lung metastases of sarcomas.
Did you know?Unlike the classic anthracyclines it carries an iodine atom on its sugar and is highly lipophilic: in animal studies it builds up in the lungs at levels more than 30 times those of doxorubicin.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Annamycin family
Isotopically labelledAnnamycin-d3Cat. No. P-A166-002Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.