Pharmacopoeial impurityAripiprazole EP Impurity ACat. No. P-A186-002CAS 22246-18-0
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Active ingredient · Aripiprazole family
Pharmaceutical analytical standardAripiprazole
Synonyms: Abilify, Abilitat, Abilify Discmelt, Discmelt, Aripiprex, Abilify MyCite, Abilify Maintena, Abilify asimtufii, OPIPZA, Abilify Digital, Abilify OD, MEZOFY
- Cat. No.
- P-A186-001
- CAS
- 129722-12-9
- Alternative CAS
- 1026778-41-5 (alternative CAS, same compound)
- Formula
- C23H27Cl2N3O2
- Molecular weight
- 448.39 g/mol
- Category
- Active ingredient (API)
An atypical antipsychotic discovered in Japan in 1988 and approved in the United States in 2002, for schizophrenia and bipolar disorder. It was the first antipsychotic to act as a partial agonist at dopamine D2 receptors.
Did you know?It is known as a 'dopamine stabiliser': where dopamine signalling is excessive it turns it down, where it is weak it boosts it, rather like a thermostat.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- AripiprazoleBP 1318
- Aripiprazole Impurity StandardBP 1319
- Aripiprazole CRSEP Y0001649
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Pharmacopoeial impurityAripiprazole USP Related Compound BCat. No. P-A186-009CAS 889443-20-3Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.