Active ingredientAtazanavirCat. No. P-A204-001CAS 198904-31-3
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Pharmacopoeial impurity · Atazanavir family
Pharmaceutical analytical standardAtazanavir EP Impurity B
Synonyms: 4-(Pyridin-2-yl)benzaldehyde, Atazanavir Pyridinyl Benzaldehyde, 4-Pyridin-2-ylbenzaldehyde, Benzaldehyde, 4-(2-pyridinyl)-
- Cat. No.
- P-A204-003
- CAS
- 127406-56-8
- Alternative CAS
- 2549012-96-4 (hydrochloride)
- Formula
- C12H9NO
- Molecular weight
- 183.21 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Atazanavir
An HIV protease inhibitor approved in the United States in 2003: it stops new virus particles from maturing and is used in combination with other antiretroviral medicines.
Did you know?It is an azapeptide, designed as an analogue of the peptide chain that HIV protease cuts: it mimics the transition state in which the bond between a phenylalanine and a proline is broken.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Atazanavir family
Active ingredientAtazanavirCat. No. P-A204-001CAS 198904-31-3
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Pharmacopoeial impurityAtazanavir EP Impurity E (Atazanavir S,R,S,S-Diastereomer)Cat. No. P-A204-005CAS 1292296-09-3
Pharmacopoeial impurityAtazanavir EP Impurity F (Atazanavir R,S,S,S-Diastereomer)Cat. No. P-A204-006CAS 1332981-14-2
Pharmacopoeial impurityAtazanavir EP Impurity G (Atazanavir S,S,S,R-Diastereomer)Cat. No. P-A204-007CAS 1332981-16-4
Pharmacopoeial impurityAtazanavir EP Impurity JCat. No. P-A204-008CAS 198904-86-8
Pharmacopoeial impurityAtazanavir EP Impurity KCat. No. P-A204-009CAS 162537-11-3Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.