Active ingredientAzilsartanCat. No. P-A238-001CAS 147403-03-0
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Impurity or related compound · Azilsartan family
Pharmaceutical analytical standardAzilsartan Impurity 34
Synonyms: Methyl 2-ethoxy-3-[[4-[2-(5-oxo-2H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate, Azilsartan Methyl Ester, Azilsartan Methyl Ester Impurity
- Cat. No.
- P-A238-050
- CAS
- 147403-52-9
- Alternative CAS
- N/A
- Formula
- C26H22N4O5
- Molecular weight
- 470.49 g/mol
- Category
- Impurity or related compound
Family: Azilsartan
An angiotensin II AT1 receptor blocker (sartan), approved in 2011 in the United States and Europe for high blood pressure. It is taken as a prodrug, azilsartan medoxomil, which the body converts into the active molecule.
Did you know?Losartan, valsartan and candesartan grip the receptor with a tetrazole ring; azilsartan swaps it for an oxadiazolone ring, an unusual chemical twist within the sartan family.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Azilsartan family
Active ingredientAzilsartanCat. No. P-A238-001CAS 147403-03-0
Isotopically labelledAzilsartan Mepixetil-d5Cat. No. P-A238-002
Isotopically labelledAzilsartan-d4Cat. No. P-A238-003CAS 1794817-45-0
Isotopically labelledAzilsartan-d5Cat. No. P-A238-004CAS 1346599-45-8
NitrosamineN-Nitroso AzilsartanCat. No. P-A238-005
NitrosamineN-Nitroso Azilsartan Impurity 1Cat. No. P-A238-006
NitrosamineN-Nitroso Azilsartan Impurity 2Cat. No. P-A238-007
NitrosamineN-Nitroso Azilsartan Impurity 3Cat. No. P-A238-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.